Parkinson’s Disease is a neurodegenerative disorder that affects predominantly dopamine-producing neurons in a specific area of the brain called substantia nigra.
Parkinson’s disease is a progressive disorder of the nervous system that affects movement. It develops slowly, sometimes starting with a barely noticeable tremor in just one hand. But while a tremor may be the most well-known sign of Parkinson’s disease, the disorder also commonly causes stiffness or slowing of movement. In the early stages of Parkinson’s disease, your face may show little or no expression, or your arms may not swing when you walk. Your speech may become soft or slurred.
The causes of parkinson’s disease certain nerve cells in the brain gradually break down or die. Many of the symptoms are due to a loss of neurons that produce a chemical messenger in your brain called dopamine. When dopamine levels decrease, it causes abnormal brain activity.
The actual cause of parkinson’s disease is unknown, but there are some causes that may contribute to it. Researchers have identified that certain genetic mutations can cause parkinson’s disease. Environmental triggers also could be a cause of Parkinson’s disease. Being exposed to certain toxins or environmental factors may increase the risk of getting Parkinson’s disease.
Another cause could be clumps of specific substances within brain cells are microscopic markers of Parkinson’s disease. These are called Lewy bodies, and researchers believe these Lewy bodies hold an important clue to the cause of Parkinson’s disease. Risk factors like aging, heredity, sex and exposure to toxins could lead to Parkinson’s disease also.
Parkinson’s disease symptoms could be different among people. Symptoms could be a tremor, slowed movement, rigid muscles,and speech changes. Tremor could be the shaking of a limb often in your hand or fingers. You may notice a back and forth movement, making simple tasks difficult and time consuming. A slowed movement could make simple tasks difficult.
Rigid muscles is stiffness may occur in any part of your body. The stiff muscles can limit your range of motion and cause you pain. You may have speech problems as a result of Parkinson’s disease. You many have a slur or hesitate before talking. Your doctor will diagnose Parkinson’s disease based on your medical history, a review of your signs and symptoms, and a neurological and physical examination.
Your doctor may order tests like blood test to rule out other conditions that may be causing your symptoms.Imaging tests such as MRI, ultrasound of the brain, SPECT and PET scans may also be used to help rule out other disorders. Parkinson’s disease can’t be cured, but medications can help control your symptoms. Medications may help you manage problems with walking, movement and tremor.
These medications increase or substitute for dopamine. Different kinds of medications may include: Carbidopa- Levodopa, Carbidopa-levodopa infusion, and dopamine agonists. Carbidopa-levodopa is the most effective parkinson’s disease medication.
It is a natural chemical that passes into your brain and is converted to dopamine. Side effects may include nausea or lightheadedness. Carbidopa-levodopa infusions is administered through a feeding tube that delivers the medication in a gel form directly to the small intestine. Dopamine agonists helps with quick relief to help the tremors . There is also surgical procedures that can be used to treat this disease.
Deep brain stimulation surgeons implant electrodes into a specific part of your brain. The electrodes are connected to a generator implanted in your chest near your collarbone that sends electrical pulses to your brain and may reduce your Parkinson’s disease symptoms.