In is newly diagnosed with hypertension, it

Intoday’s medical world, there are multiple options for treatment ofhypertension.  If a patient is newlydiagnosed with hypertension, it was common for the patient to be started on abeta-blocker.  Beta-blockers were previouslythe most commonly prescribed medication due to their mechanism of action and showinga minimal chance of reaction to patients. Treatments have changed over time to find that beta-blockers are lesspreferred as they were in the past, but has found an increase in use forvarious medical conditions.  Theuse of beta-blockers has decreased with time.

 This is due to multiple factors.  One of the factors is that optimizing thedosage can be difficult for patients.  Anotherfactor is that some beta blocker may cross the blood brain barrier which may showeffects of the central nervous system.  Athird factor is that interactions of beta-blockers with other medications.

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  This may result is bradycardia.  Finally, a fourth and final factor is thatthere is a possibility of an accidental overdose.  This can be treated with the obvious epi oratropine, but it may able be treated with a large variety of other medicationssuch as glucagon, insulin, or calcium. This accidental overdose may possible be related back to medicationoptimization difficulties.Eventhough the use of beta-blockers has decreased with time, its usage hasincreased with certain medical conditions. Beta-blockers work well when used in conjunction with other cardiacrelated medications for vasodilation to reduce tachycardia.  Where once they were thought of to beinhibiting to cardiac patients, they are now considered detrimental to patientswith heart failure and reduced ejection fracture.

  Multiple studies have found that patient hadbetter survival rates with angina and tachycardia if they were to use abeta-blocker.Beta-blockerswere initially used only for hypertension.  But what developed over time was patients thatwere using beta-blockers were noting a reduction in symptoms from secondary medicalconditions.  Patient were getting relieffrom migraines, hypothyroidism, intraocular pressure, tremors, and manyadditional medical conditions.

  This maybe in part to beta-blockers having various pharmacological effects on variousareas of the body.  Some have intrinsic sympathomimeticactivity, while others cause vasodilation, and others have a significantantioxidant effect.Whatis not well known is that beta-blockers have a rich history that has existedever since their creation in the 1960’s. Beta-blockers have won the Nobel Prize in 1998.  This was due to it being the first treatment forangina in over 100 years since the creation of nitroglycerine.

  It has also been in multiple medicationtrials that were named with astrologic names (Gemini, Copernicus, and Comet).  Also, beta-blockers have been banned by theWorld Anti-Doping Agency.  Athletes thatparticipate in archery, automobile racing, billiards, darts, golf, ski jumping,and underwater sports are banned from using beta-blockers.Ancientraces believed that a person needed to have balance of the “body humors” foroptimal health.  The use of beta-blockersfor the appropriate patient is a reaffirmation of that belief.  Even though it is not as frequently usedtoday, the right beta-blocker for the job can do a lot for the health of thepatient.



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